Key goals include organizing a high-level visit between the two nations and hosting the first round of an expanded strategic partnership dialogue in Tashkent. This effort aims to strengthen ties with the incoming U.S. administration and reinforce Uzbekistan's strategic importance in Central Asia.

Uzbekistan intends to intensify cooperation under the "C5+1" regional framework, which involves the five Central Asian countries and the U.S. The plans include ministerial meetings, working group sessions, and preparing for a 10th-anniversary summit in Samarkand.

Uzbekistan is also set to expand parliamentary cooperation by hosting leading U.S. Congress members and boosting trade and investment ties through business forums, exhibitions, and targeted investor outreach. Security collaboration will remain a key focus, with efforts to maintain Uzbekistan's high standing in U.S. human rights reports.

Additionally, the program highlights plans for increased cooperation in education, science, healthcare, and environmental protection. Joint initiatives include university partnerships, English language teaching programs, and ecological projects.