According to the airline, today Uzbekistan Airways will operate regular flights to Istanbul from Tashkent, Samarkand, Fergana and Urgench. Flights are operated every day on modern Boeing and Airbus aircraft.

Flights to Istanbul will operate according to the following weekly schedule:

- from Fergana, flights are performed three times a week – on Mondays, Wednesdays and Saturdays;
- from Samarkand, three times a week – on Mondays, Wednesdays and Fridays;
- from Urgench, twice a week – on Tuesdays and Fridays;
- flights from Tashkent to Istanbul are operated daily.