Rahmatulloh Sayfuddinov is one of the students of the late Sheikh Muhammad Sodiq Muhammad Yusuf.

During his career, he worked as an imam-khatib at the Khujja Alambardor and Minor mosques in Tashkent (2014-2015), taught at the Tashkent Islamic Institute named after Imam Bukhari. 

Prior to his appointment, Rahmatulloh Sayfuddinov was the chief of the Yunusabad district and imam-khatib of the Mirza Yusuf mosque.

Earlier, it was reported that Nuriddin Kholiknazarov, who has been the chief imam-khatib of Tashkent since 2019, has been elected chairman of the Muslim Board of Uzbekistan.